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observed increased time-dependent sensitivity to necroptosis in ACSL4-knockout cells using CRISPR/Cas9-based genome-editing technology ( Given the complexity of CNS trauma, the biochemical regulation and sensitivity of various cell types, such as oligodendrocytes, microglia, astrocytes, or neurons, to ferroptosis also require discussion

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Although the sample size is small, monotherapy of emibetuzumab was well tolerated and showed certain anti-tumor activity (Sakai et al., 2017)